{"id":7553,"date":"2026-06-25T17:33:59","date_gmt":"2026-06-25T14:33:59","guid":{"rendered":"https:\/\/oncomsi.com\/tedavilerimiz\/hipertermi\/"},"modified":"2026-09-29T18:35:27","modified_gmt":"2026-09-29T15:35:27","slug":"hyperthermia","status":"publish","type":"services","link":"https:\/\/oncomsi.com\/en\/treatments\/hyperthermia\/","title":{"rendered":"Hyperthermia"},"content":{"rendered":"\t\t
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Hyperthermia<\/h1> \r\n\r\n <\/div>\r\n\r\n \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Hyperthermia is a complementary cancer treatment method based on the controlled heating of tumor tissue to 39-44 \u00b0C<\/strong>. Cancer cells are more sensitive to heat than healthy cells, and this sensitivity is used to increase the effectiveness of chemotherapy and radiotherapy. This page explains how hyperthermia works, which types exist and how it is applied at ONCOMSI.<\/p>

What Is Hyperthermia?<\/h2>

Hyperthermia is the oncologic application of thermotherapy, meaning “treatment with heat”<\/strong>. By heating the targeted tumor tissue or the whole body in a controlled way, it aims to weaken cancer cells biologically. It is different from hyperthermia in the sense of heat stroke: hyperthermia in cancer treatment is applied under physician supervision, with dedicated devices and within a measured temperature range.<\/p>

Hyperthermia is not a cancer treatment on its own. It is applied as an evidence-based complementary protocol that increases the effectiveness of core treatments such as chemotherapy and radiotherapy. The NCI (National Cancer Institute) and academic reviews on NCBI Bookshelf document the synergy of hyperthermia with chemotherapy and radiotherapy.<\/p>

The History and Scientific Background of Hyperthermia<\/h2>

The foundations of modern hyperthermia research were laid in the 19th century<\/strong>. In 1868, the German physician W. Busch observed that bacterial fever caused tumor regression in a patient with soft tissue sarcoma who had an erysipelas infection. In 1892, the American surgeon William B. Coley turned a similar observation into a systematic treatment approach and developed the mixed bacterial vaccine known as “Coley’s toxins”. The full story is told in Coley’s toxins and the history of hyperthermia<\/a>.<\/p>

Coley recorded that fever (39-40 \u00b0C) provided sustained immune activation and was a critical factor in tumor regression. The philosophical origin is even older: the Greek philosopher Parmenides is quoted as saying, “Give me the power to raise the body’s temperature and I will heal every disease.” Today, hyperthermia is recognized by several European cancer societies as a complementary arm of cancer treatment.<\/p>

How Does Hyperthermia Work?<\/h2>

The effectiveness of hyperthermia comes from cancer cells being more sensitive to heat<\/strong> than healthy cells. Tumor tissue lives in a more acidic environment, with less oxygen and a chaotic blood vessel structure. These differences allow heat to act more strongly on cancer cells than on healthy tissue.<\/p>